Naturalproductman’s Blog

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Archive for the ‘Steroids’ Category

Cucurbitacins make wild cucumbers bitter

Posted by naturalproductman on November 27, 2014

Yi Shang and co-workers at the Chinese Academy of Agricultural Sciences have reported in Science on the genes that make cucmbers bitter and the selection process that made domestic cucumbers not bitter – it had to do with the transcription factor called Bitter fruit.

Science paper

Posted in Food, Steroids | Leave a Comment »

Plakinamines N and O

Posted by naturalproductman on November 4, 2014

Kirk Gustafson and co-workers from the NCI have reported in JNP on the isolation of plakinamines N and O.
plakinamine

JNP paper

Posted in Alkaloids, Cancer, colon, Steroids | Leave a Comment »

Swinhoeisterol

Posted by naturalproductman on April 3, 2014

Wen Zhang and co-workers from Second Military Medical University in China have reported in Organic Letters on the isolation of swinhoeisterol.
swinhoeisterol

OL paper

Posted in Protein Targets, Seven-Membered Rings, Steroids | Leave a Comment »

19-Hydroxysarmentogenin synthesis

Posted by naturalproductman on April 18, 2013

Masayuki Inoue and co-workers from University of Tokyo have reported in ACIE on a synthesis of 19-hydroxysarmentogenin.

steroid

ACIE paper

Posted in Methodology, Steroids, Total Synthesis | Leave a Comment »

C-H amination of C12-position

Posted by naturalproductman on January 31, 2013

Shuji Yamashita and co-workers from Tohoku University have reported in Tetrahedron Letters on a C-H amination of the C12-position of steroids.

amination

Tetrahedron Letters paper

Posted in C-H activation, Methodology, Steroids | Leave a Comment »

Andrastin C synthesis

Posted by naturalproductman on November 19, 2012

Masahiro Toyota and co-workers from Tohoku University have reported in JOC on the synthesis of andrastin C.

andrastin C

JOC paper

Posted in Cascade Reactions, Methodology, Ring forming, Steroids | Leave a Comment »

A rearranged steroids from a mushroom

Posted by naturalproductman on October 2, 2012

Hirokazu Kawagishi and co-workers from Shizuoka University have reported in ACIE on the isolation of strophasterols A-D.

D ring

ACIE paper

Posted in Steroids | Leave a Comment »

Desmosterol needed for HCV

Posted by naturalproductman on April 11, 2012

Priscilla Yang and co-workers from Harvard have reported in JACS on the identification of desmosterol needed for heptatitis C virus protein expression and viral genomic RNA.  I wonder why JACS has a green text background now in the articles instead of blue…

desmosterol

JACS paper

Posted in Chemical Biology, Diseases, Hepatitis C, Metabolomics, Steroids | Leave a Comment »

Viridin progress

Posted by naturalproductman on February 20, 2012

Peter Jacobi and colleague from Dartmouth University have reported in Tetrahedron Letters on their approach towards viridin.

viridin
TL paper

Posted in Cascade Reactions, Methodology, Steroids | Leave a Comment »

Ceposides

Posted by naturalproductman on January 17, 2012

Virginia Lanzotti and co-workers from Università degli Studi di Napoli Federico II in Italy have reported in Phytochemistry on the isolation of antifungal saponins from white onions.

white onions

Phytochemistry paper

Posted in Antifungal, Glycosides, Steroids | Leave a Comment »

 
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