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Archive for the ‘Terpenes’ Category

Taiwaniadducts B, C, and D syntheses

Posted by naturalproductman on June 3, 2014

Ang Li and co-workers from SIOC have reported in JACS on the syntheses of taiwaniadducts B, C, and D.

taiwaniadducts

JACS paper

Posted in Europium, Lanthanides, Methodology, Terpenes, Terpenoids, Total Synthesis | Leave a Comment »

Decaturin C synthesis

Posted by naturalproductman on September 19, 2012

Hirosato Takikawa and co-workers at Kobe University have reported in Tetrahedron on the synthesis of decaturin C, a compound with insecticidal properties. I was curious about the hemiketal formation – whether or not the hemiketal is formed completely or it is in equilibrium with the ketone.

decaturin C

Tetrahedron paper

Posted in Methodology, Polyketides, Terpenes, Total Synthesis | Leave a Comment »

Abiestetranes A and B

Posted by naturalproductman on August 6, 2012

Wei-Dong Zhang and co-workers from have reported in Tetrahedron on the isolation of some spirocyclic tetraterpenes, abiestetranes A and B.

tetraterpenes

Tetrahedron paper

Posted in Cancer, Spirocycles, Terpenes | Leave a Comment »

Manoalide vs. HCV

Posted by naturalproductman on March 30, 2012

Nobuyoshi Akimitsu and co-workers from the University of Tokyo have reported on the identification of manoalide A as an inhibitor for heptatitis C virus NS3 helicase.
manoalide

JNP paper

Posted in Diseases, Enzymes, Hepatitis C, Protein Targets, Proteins, Terpenes | Leave a Comment »

Anisatin synthesis

Posted by naturalproductman on February 29, 2012

Tohru Fukuyama  and co-workers have reported in Organic Letters on the synthesis of anisatin via a Diels-Alder.

Diels Alder

OL paper

Posted in Diels-Alder, Methodology, Named Reactions, Terpenes | Leave a Comment »

Saudin synthesis

Posted by naturalproductman on November 21, 2011

Robert Boeckman and co-workers at the University of Rochester have reported in Tetrahedron on the synthesis of saudin.

saudin

Tetrahedron paper

Posted in Asymmetric, Cascade Reactions, Claisen rearrangement, Methodology, Named Reactions, Terpenes | Leave a Comment »

A new C35-terpene cyclase

Posted by naturalproductman on June 7, 2011

Tsutomu Sato and co-workers from Niigata University have reported in JACS on the identification of a terpene cyclase enzyme that cyclized a C35 terpene (sesquarterpene).

C35

JACS paper

Posted in Chemical Biology, Enzymatic, Methodology, Sesquarterpenes, Terpenes | Leave a Comment »

Epi-cochlioquinone A Synthesis

Posted by naturalproductman on September 20, 2010

Kuniaki Tatsuta and co-workers from Waseda University have published in Tetrahedron Letters on a total synthesis of epicochlioquinone A featuring a vinylogous Michael reaction and many more.

synthesis

TL paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Michael, Named Reactions, Pericyclic reactions, Terpenes | Leave a Comment »

A Ring Contraction Approach for Taiwaniaquinone

Posted by naturalproductman on June 14, 2010

Karl Gademann and co-workers at the University of Basel in Switzerland have published in a ring contraction approach – an intramolecular benzilic acid rearrangement – to access the taiwaniaquinone carbon skeleton.

taiwaniaquinone

Chemistry – a European Journal paper

Posted in Cascade Reactions, Methodology, Ring contraction, Terpenes | Leave a Comment »

 
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