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Archive for the ‘Terpenoids’ Category

Taiwaniadducts B, C, and D syntheses

Posted by naturalproductman on June 3, 2014

Ang Li and co-workers from SIOC have reported in JACS on the syntheses of taiwaniadducts B, C, and D.

taiwaniadducts

JACS paper

Posted in Europium, Lanthanides, Methodology, Terpenes, Terpenoids, Total Synthesis | Leave a Comment »

Ingenol synthesis

Posted by naturalproductman on April 18, 2014

Phil Baran and co-workers reported in JACS on their synthesis of ingenol.

ingenol

JACS paper

Posted in Terpenoids, Total Synthesis | Leave a Comment »

Crotogoudin synthesis

Posted by naturalproductman on August 30, 2013

Erick Carreira and colleague have reported in ACIE on the synthesis of crotogoudin.

crotogoudin

ACIE paper

Posted in Methodology, Terpenoids, Total Synthesis | Leave a Comment »

Asperterpenoid A

Posted by naturalproductman on January 31, 2013

Zhigang She and co-workers from Sun-Yat Sen University have reported in Organic Letters on the isolation of asperterpenoid A, which had an IC50 value of 2.2 micromolar against Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB).

ABCDE

OL paper

Posted in Protein Targets, protein tyrosine phosphatase 1B (PTP1B), Terpenoids | Leave a Comment »

Amphilectene synthesis

Posted by naturalproductman on November 16, 2012

Ryan Shenvi and colleague at Scripps have reported in JACS on the synthesis of amphilectene, an antimalarial compound.

amphilectene

JACS paper

Posted in Diseases, Malaria, Terpenoids, Total Synthesis | Leave a Comment »

Indium bromide cyclization

Posted by naturalproductman on October 2, 2012

Teck-Peng Loh and co-workers from the University of Science and Technology have reported in ACIE on the synthesis of moluccanic acid methyl ester through a Prins-polyene cyclization using indium (III) bromide.

cascade

ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Prins, Terpenoids, Total Synthesis | Leave a Comment »

FR182877 progress

Posted by naturalproductman on April 4, 2012

Masahisa Nakada and co-workers from Waseda University have reported in Organic Letters on their progress towards FR182877.
polycycle

OL paper

Posted in Methodology, Terpenoids | 2 Comments »

Vigulariol and sclerophytin A syntheses

Posted by naturalproductman on August 19, 2011

Michael Crimmins and co-workers at UNC have reported in Organic Letters on the syntheses of two similar looking natural products, vigulariol and sclerophytin A.

vigulariol

OL paper

Posted in Diels-Alder, Methodology, Named Reactions, Terpenoids, Wittig | Leave a Comment »

Sterostreins

Posted by naturalproductman on August 18, 2011

Terpenoids were isolated from a fungus called sterostreins A-E, which had antimalarial activity (IC50 2.3 micrograms/mL).
antimalarial

OL paper

Posted in Terpenoids | Leave a Comment »

Dotofide

Posted by naturalproductman on May 20, 2011

Gabriele Konig and co-workers have reported in the European Journal of Organic Chemistry on the isolation of a terpenoid from a sea slug.

dotofide

European JOC paper

Posted in Terpenoids | Leave a Comment »

 
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