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Archive for the ‘Tetrahydrofuran’ Category

Teurilene through epoxide ring opening

Posted by naturalproductman on February 22, 2013

Tomas Martin and co-workers from the Universidad de La Laguna in Spain have reported in ACIE on the synthesis of teurilene through an epoxide ring opening cascade.

epoxide

ACIE paper

Posted in Cascade Reactions, Methodology, Tetrahydrofuran, Total Synthesis | Leave a Comment »

Heronapyrrole C synthesis

Posted by naturalproductman on July 20, 2012

Christian Stark and colleague at the Universitat Hamburg have reported in Organic Letters on the synthesis of heronapyrrole C.

heronapyrrole C

OL paper

Posted in Alkaloids, Asymmetric, Methodology, Tetrahydrofuran, Total Synthesis | Leave a Comment »

Shi epoxidation approach for glabrescol

Posted by naturalproductman on July 20, 2012

Jin Qu and co-workers from Nankai University have reported in Organic Letters on a synthesis of a polytetrahydrofuranyl compound using Shi epoxidation of a polyolefin intermediate.

cascade

OL paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Polyenes, Shi epoxidation, Tetrahydrofuran, Total Synthesis | Leave a Comment »

2 routes for elatenyne and is DFT going to be a standard for natural product structure assignment?

Posted by naturalproductman on July 3, 2012

Deukjoon Kim (Seoul National University) and Jonathon Burton (University of Oxford) and co-workers have reported in JACS on a synthesis of elatenyne.

elatenyne

JACS paper

Posted in Cascade Reactions, Methodology, Tetrahydrofuran, [2+2] | Leave a Comment »

IKD-8344 synthesis

Posted by naturalproductman on April 11, 2012

Yikang Wu and co-worker from Shanghai Institute of Organic Chemistry have reported in ACIE on a synthesis of a natural product containing tetrahydrofurans, IKD-8344.

tetrahydrofuran

ACIE paper

Posted in Methodology, Tetrahydrofuran, Total Synthesis | Leave a Comment »

Access to bis-THF rings

Posted by naturalproductman on February 8, 2012

Hiromichi Fujioka and co-workers at Osaka University have reported in Organic Letters on a method to synthesize bis-tetrahydrofurans from a diol.

iodonium
OL paper

Posted in Cascade Reactions, Methodology, Ring forming, Tetrahydrofuran | Leave a Comment »

Cytotoxic acetogenins

Posted by naturalproductman on November 10, 2011

Xiang Li and co-workers from Nanjing University of Chinese Medicine have isolated some bistetrahydrofurans.

bis tetrahydrofuran

JNP paper

Posted in Acetogenins, Cancer, Tetrahydrofuran | Leave a Comment »

Pestalotheols

Posted by naturalproductman on September 18, 2011

Karsten Krohn and co-workers at the University of Paderborn have reported in European JOC on the isolation of some biologically active tetrahydrofurans.

pestalotheols

European JOC paper

Posted in Antibiotics, Tetrahydrofuran | Leave a Comment »

Orthodiffenes A-D

Posted by naturalproductman on December 7, 2010

Biswanath Das and co-workers at IICT have published in Tetrahedron Letters on the isolation of orthodiffenes A-D. Orthodiffene A had an IC50 value of 3.66 micrograms/mL against HL-60 cell lines.

orthodiffenes

 

TL paper

Posted in Tetrahydrofuran, Tetrahydropyran | Leave a Comment »

Osmium Catalyzed Oxidative Cyclization

Posted by naturalproductman on September 7, 2010

Timothy Donohoe and co-workers at the University of Oxford have published in Synlett on an osmium catalyzed oxidative cyclization of a vinyl silane tethered with an alcohol to form substituted tetrahydrofurans.

oxidative cyclization

Synlett paper

Posted in Cascade Reactions, Methodology, Osmium, Tetrahydrofuran, Transition Metal | Leave a Comment »

 
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