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Archive for the ‘Total Synthesis’ Category

Lyngbyaloside B synthesis

Posted by naturalproductman on November 16, 2014

Hauruhiko Fuwa and co-workers at Tohoku University have reported in ACIE on the synthesis of lyngbyaloside B.

synthesis

ACIE paper

Posted in Methodology, Total Synthesis | Leave a Comment »

Structure revision through total synthesis

Posted by naturalproductman on November 16, 2014

Rosario Hernández-Galán and co-workers at Universidad de Cádiz in Spain have reported in JOC on the synthesis of cinbotolide and the revised structure through total synthesis looks completely different from the proposed macrocyclic structure.

cinbotolide

JOC paper

Posted in Structural Reassignment, Total Synthesis | Leave a Comment »

Rubriflordilactone A synthesis

Posted by naturalproductman on November 14, 2014

Ang Li and co-workers from SIOC have reported in JACS on the synthesis of rubriflordilactone A.
rubriflordilactone A

JACS paper

Posted in Methodology, Total Synthesis | Leave a Comment »

Phenolic coupling for morphine

Posted by naturalproductman on November 10, 2014

Matthew Gaunt and co-workers from the University of Cambridge have reported in ACIE on the formal synthesis of morphine through an oxidative phenolic coupling.

morphine

ACIE paper

Posted in Alkaloids, Cascade Reactions, Hypervalent Iodine, Methodology, Total Synthesis | Leave a Comment »

Ascospiroketal A synthesis

Posted by naturalproductman on November 8, 2014

Robert Britton and co-workers from Simon Fraser University have reported in ACIE on the synthesis of ascospiroketal A through a silver cascade reaction.

silver

ACIE paper

Posted in Cascade Reactions, Methodology, Silver, Total Synthesis, Transition Metal | Leave a Comment »

Neopeltolide through metathesis

Posted by naturalproductman on November 8, 2014

Hoveyda and co-workers have reported in ACIE on the synthesis of neopeltolide.

metathesis

ACIE paper

Posted in Metathesis, Methodology, Ruthenium, Total Synthesis, Transition Metal | Leave a Comment »

Dibefurin synthesis

Posted by naturalproductman on November 8, 2014

Dirk Trauner and co-workers have reported in ACIE on the synthesis of dibefurin.

dibefurin

ACIE paper

Posted in Protein Targets, Total Synthesis | Leave a Comment »

Q-Z domain of maitotoxin

Posted by naturalproductman on November 6, 2014

Nicolaou and co-workers have reported in the synthesis of a Q-Z domain of maitotoxin.

 

maitotoxin

JACS paper

Posted in Polycyclic, Polyether, Total Synthesis | Leave a Comment »

Myrioneurinol synthesis

Posted by naturalproductman on November 4, 2014

Steven Weinreb and colleague at Penn State have reported in ACIE on the synthesis of myrioneurinol.

alkaloid

ACIE paper

Posted in Total Synthesis, Diseases, Malaria | Leave a Comment »

Alkaloid syntheses

Posted by naturalproductman on November 4, 2014

Xiaoguang Lei and co-workers from Tianjin University have reported in ACIE on the syntheses of huperzine and lycopladines.

alkaloids

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

 
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