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Archive for the ‘Total Synthesis’ Category

Lipiarmycin synthesis

Posted by naturalproductman on November 28, 2014

Jieping Zhu and co-workers at CNRS have reported in ACIE on the synthesis of lipiarmycin.

polyketide

ACIE paper

Posted in Glycosides, Methodology, Polyketides, Total Synthesis | Leave a Comment »

Plantazolicin A synthesis

Posted by naturalproductman on November 28, 2014

Steven Ley and co-workers at the University of Cambridge have reported in ACIE on the syntheses of plantazolicins A and B.

thiazole

ACIE paper

Posted in Methodology, Oxazoles, Thiazoles, Total Synthesis | Leave a Comment »

Mogolides A and B syntheses

Posted by naturalproductman on November 28, 2014

Yefeng Tang and co-workers from Tsinghua University have reported in ACIE on the synthesis mogolides A and B.

biomimetic

ACIE paper

Posted in Diels-Alder, Dimer, Named Reactions, Polyketides, Total Synthesis | Leave a Comment »

Fidaxomicin synthesis

Posted by naturalproductman on November 28, 2014

Karl Gademann and co-workers at the University of Basel have reported in ACIE on the synthesis of
fidaxomicin
ACIE paper

Posted in Methodology, Named Reactions, Polyketides, Total Synthesis, Yamaguchi macrolactonization | Leave a Comment »

Alsmaphorazine D synthesis

Posted by naturalproductman on November 27, 2014

Hanfeng Ding and co-workers have reported in ACIE on the synthesis of alsmaphorazine D.
indole

ACIE paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Lyngbyaloside B synthesis

Posted by naturalproductman on November 16, 2014

Hauruhiko Fuwa and co-workers at Tohoku University have reported in ACIE on the synthesis of lyngbyaloside B.

synthesis

ACIE paper

Posted in Methodology, Total Synthesis | Leave a Comment »

Structure revision through total synthesis

Posted by naturalproductman on November 16, 2014

Rosario Hernández-Galán and co-workers at Universidad de Cádiz in Spain have reported in JOC on the synthesis of cinbotolide and the revised structure through total synthesis looks completely different from the proposed macrocyclic structure.

cinbotolide

JOC paper

Posted in Structural Reassignment, Total Synthesis | Leave a Comment »

Rubriflordilactone A synthesis

Posted by naturalproductman on November 14, 2014

Ang Li and co-workers from SIOC have reported in JACS on the synthesis of rubriflordilactone A.
rubriflordilactone A

JACS paper

Posted in Methodology, Total Synthesis | Leave a Comment »

Phenolic coupling for morphine

Posted by naturalproductman on November 10, 2014

Matthew Gaunt and co-workers from the University of Cambridge have reported in ACIE on the formal synthesis of morphine through an oxidative phenolic coupling.

morphine

ACIE paper

Posted in Alkaloids, Cascade Reactions, Hypervalent Iodine, Methodology, Total Synthesis | Leave a Comment »

Ascospiroketal A synthesis

Posted by naturalproductman on November 8, 2014

Robert Britton and co-workers from Simon Fraser University have reported in ACIE on the synthesis of ascospiroketal A through a silver cascade reaction.

silver

ACIE paper

Posted in Cascade Reactions, Methodology, Silver, Total Synthesis, Transition Metal | Leave a Comment »

 
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