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Archive for the ‘Total Synthesis’ Category

Haouamine B pentaacetate synthesis

Posted by naturalproductman on October 11, 2014

Hidetoshi Tokuyama and co-workers from Tohoku University have reported in ACIE on the synthesis of haouamine B pentaacetate.

haouamine B

ACIE paper

Posted in Alkaloids, Structural Reassignment, Total Synthesis | Leave a Comment »

Hapalindole alkaoid syntheses

Posted by naturalproductman on October 11, 2014

Ang Li and co-workers from SIOC have reported in ACIE on the syntheses of hapalindole compounds.

hapalindole

ACIE paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Δ9-THC synthesis

Posted by naturalproductman on October 11, 2014

Erick Carreira and co-workers have reported in ACIE on the synthesis of dehydrotetrahydrocannabinol.

THC

ACIE paper

Posted in Dual Catalysis, Methodology, Total Synthesis | Leave a Comment »

N-methylwelwitindolinone B isothiocyanate synthesis

Posted by naturalproductman on October 11, 2014

Neil Garg and co-workers reported the synthesis of N-methylwelwitindolinone B isothiocyanate in JACS.

alkaloid

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Unified strategies are in

Posted by naturalproductman on October 7, 2014

Jieping Zhu and co-workers from CNRS have reported in JACS on the syntheses of some alkaloids, goniomitine, 1,2-dehydroaspidospermidine, aspidospermidine, vincadifformine, and kopsihainanine A.

 

JACS paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Rakicidin A synthesis

Posted by naturalproductman on October 7, 2014

Yue Chen and co-workers from Nankai University have reported in JACS on the synthesis of rakicidin A, which has inhibitory activity towards cancer stem cells.

 

 

JACS paper

Posted in Macrocycles, Total Synthesis | Leave a Comment »

Aspeverin synthesis

Posted by naturalproductman on August 30, 2014

Adam Levinson at Sloan Kettering has reported in Organic Letters on the synthesis of aspeverin. Interestingly, Danishefsky was acknowledged for the mentorship but not included in the authors list. I wonder if this is a new kind of way to publish.

aspeverin

OL paper

Posted in Alkaloids, Hypervalent Iodine, Methodology, Total Synthesis | 3 Comments »

Steviol, hetidine, isoatisine syntheses

Posted by naturalproductman on August 30, 2014

Phil Baran and co-workers have reported in JACS on the syntheses of steviol, hetidine, and isoatisine.

alkaloids

JACS paper

Posted in Alkaloids, C-H activation, Methodology, Total Synthesis | Leave a Comment »

Basiliolide B synthesis

Posted by naturalproductman on August 30, 2014

Chi-Sing Lee and co-workers at Shen Zhen University have reported in ACIE on the synthesis of basioli
basiliolide B

ACIE paper

Posted in Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Myceliothermophins C, D, and E

Posted by naturalproductman on August 30, 2014

Nicolaou and co-workers have reported in ACIE on the syntheses of myceliothermophins C, D, and E.

myceliothermophins

ACIE paper

Posted in Methodology, Total Synthesis | Leave a Comment »

 
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