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Archive for the ‘Total Synthesis’ Category

Gymnothelignan N synthesis

Posted by naturalproductman on August 18, 2014

Xuegong She and co-workers from Lanzhou University have reported in Organic Letters on the synthesis of

Friedel-Crafts

OL paper

Posted in Friedel-Crafts, Named Reactions, Spirocycles, Spirocyclic centers, Total Synthesis | Leave a Comment »

(+)-Procyanidin A2 and (+)-Cinnamtannin B1 syntheses

Posted by naturalproductman on August 18, 2014

Keisuke Suzuki and co-workers from Tokyo Institute of Technology have reported in ACIE on the synthesis of (+)-procyanidin A2 and (+)-cinnamtannin B1.

aromatic

ACIE paper

Posted in Aromatic, Total Synthesis | Leave a Comment »

Merochlorins A and B syntheses, enzymatically

Posted by naturalproductman on August 18, 2014

Bradley Moore and Phil Baran’s groups teamed up to synthesize merochlorin A and B.

Merochlorin

ACIE paper

Posted in Biosynthesis, Chemical Biology, Enzymatic, Polyketides, Total Synthesis | Leave a Comment »

Delta12-prostaglandin J3 synthesis

Posted by naturalproductman on August 18, 2014

Nicolaou and co-workers have reported in ACIE on the synthesis of delta12-prostaglandin J3.

prostaglandin J3

ACIE paper

Posted in Aldol, Cancer, leukemia, Methodology, Polyenes, Prostaglandins, Total Synthesis | Leave a Comment »

Cavicularin synthesis

Posted by naturalproductman on August 18, 2014

Christopher Beaudry and colleague at Oregon State have reported in ACIE on the synthesis of cavicularin through a Diels-Alder with a vinyl sulfone dienophile.

Diels Alder

ACIE paper

Posted in Aromatic, Diels-Alder, Methodology, Total Synthesis | Leave a Comment »

Viridicatumtoxin B synthesis

Posted by naturalproductman on August 18, 2014

Nicolaou and co-workers have reported in JACS on the synthesis of viridicatumtoxin B.

polyketide

JACS paper

Posted in Methodology, Polyketides, Total Synthesis | Leave a Comment »

Aluminum porphyrin

Posted by naturalproductman on July 27, 2014

George O’Doherty and co-workers from Northeastern University have reported in JACS on an aluminum catalyzed beta-lactone synthesis from epoxides.

aluminum

JACS paper

Posted in Cascade Reactions, Lactones, Methodology, Total Synthesis | Leave a Comment »

Claisen-Diels-Alder cascade to spirooliganones A and B

Posted by naturalproductman on July 16, 2014

Rongbiao Tong and co-workers from the Hong Kong University of Science and Technology have reported in Org Lett on a slick reaction to form spirooliganones.

 
spirooliganones

OL paper

Posted in Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Total Synthesis | Leave a Comment »

Crinipellin A synthesis

Posted by naturalproductman on July 12, 2014

Hee-Yoon Lee and co-workers at KAIST have reported in JACS on the synthesis of crinipellin A.

synthesis

JACS paper

Posted in Allenes, Methodology, Total Synthesis | Leave a Comment »

Kuwanons I and J and Brosimones A and B syntheses

Posted by naturalproductman on July 12, 2014

Xiaoguang Lei and co-workers at Peking University have reported in ACIE on the synthesis of kuwanons I and J.
aromatic

ACIE paper

Posted in Antioxidants, Aromatic, Total Synthesis | Leave a Comment »

 
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