Naturalproductman’s Blog

Hey, is that a natural product?!

Photoredox cross-coupling

Posted by naturalproductman on August 31, 2015

Larry Overman and co-workers reported in JACS on a photoredox coupling between tertiary alcohols and electron deficient olefins.

JACS paper

Posted in cross coupling, Light Mediated, Methodology | Leave a Comment »

Exotines A and B

Posted by naturalproductman on August 28, 2015

Yong Jiang and co-workers from Peking University have reported in Organic Letters on the isolation of exotines A and B, which inhibited nitric oxide production.

exotines

OL paper

Posted in Coumarins, Indoles | Leave a Comment »

Conolutinine synthesis

Posted by naturalproductman on August 28, 2015

Weiqing Xie and co-workers from Northwest A&F University have reported in Organic Letters on the synthesis of conolutinine.
conolutinine

OL paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Aryl bromide and aryl triflate cross coupling with Ni and Pd

Posted by naturalproductman on August 28, 2015

Daniel Weix and co-workers have reported in Nature on a multimetallic cross coupling between an aryl triflate and aryl bromide using palladium and nickel.

Nature paper

Posted in Cooperative Catalysis, cross coupling, Methodology, Nickel, Palladium, Transition Metal | Leave a Comment »

Fe-catalyzed [2+2]

Posted by naturalproductman on August 28, 2015

Paul Chirik and co-workers from Princeton have reported in Science on an iron catalyzed [2+2] cycloaddition.

Science paper

Posted in Cycloaddition, Iron, Transition Metal, [2+2] | Leave a Comment »

Regioselective acylation

Posted by naturalproductman on August 28, 2015

Takeo Kawabata and co-workers from Kyoto University have reported in ACIE on the synthesis of multifidosides through a regioselective acylation.

acylation

ACIE paper

Posted in Glycosides, Methodology, Regioselective, Total Synthesis | Leave a Comment »

Leucoridine synthesis

Posted by naturalproductman on August 28, 2015

Rodrigo Andrade and co-workers from Temple University have reported in ACIE on the synthesis of

Diels-Alder

ACIE paper

Posted in Alkaloids, Diels-Alder, Dimer, Methodology, Named Reactions, Total Synthesis | Leave a Comment »

Amine trapping

Posted by naturalproductman on August 28, 2015

John Wolfe and co-workers have reported in JACS on a palladium catalyzed carboamination.

indane

JACS paper

Posted in Asymmetric, Methodology, Palladium, Transition Metal | Leave a Comment »

Fijiolide A synthesis

Posted by naturalproductman on August 27, 2015

Nicolai Cramer and colleague from EPFL have reported in JACS on the synthesis of fijiolide A.

fijiolide

JACS paper

Posted in Aromatic, Macrolides, Total Synthesis | Leave a Comment »

Pericoannosin A

Posted by naturalproductman on August 27, 2015

Jungui Dai and co-workers from Chinese Academy of Medical Sciences have reported in Organic Letters on the isolation of pericoannosin A.

funal

OL paper

Posted in Antiviral, Polyketides | Leave a Comment »

 
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