Naturalproductman’s Blog

Hey, is that a natural product?!

A New Tetrahydrofuranyl Synthesis

Posted by naturalproductman on February 26, 2009

Tristan Lambert at Columbia University has come up with yet another clever methodology. Using Bismuth as the catalyst, he starts with an enal and reacts with a nucleophile. The nucleophile attacks the aldehyde and a hydroalkoxylation follows. It’s a very neat and simple looking protocol.

Lambert's hydroalkoxylation reaction

Org. Lett.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

 
%d bloggers like this: