Naturalproductman’s Blog

Hey, is that a natural product?!


Posted by naturalproductman on February 27, 2009

Palau’amine, isolated by the group of the late Paul Scheuer in the University of Hawaii at Manoa in 1993, is still a desirable target for synthetic chemists around the world.  Many people are working on it and it has yet to be synthesized by anybody.  The stereochemistry of the cyclopentane core is controversial.  It is an oroidin dimer natural product just like massadine, however, massadine has been synthesized by the Baran group at Scripps last year.

JACS isolation

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