Naturalproductman’s Blog

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Cembrane-Africanane Terpenoids are Hybrid Metabolites

Posted by naturalproductman on June 24, 2009

Marc Slattery and Haidy Kamel et al at the University of Mississippi reported recently in the Journal of Natural Products on the isolation of five new terpenoids from the hybrid of Sinularia maxima × S. polydactyl soft corals.  Hybridization of plants leads to very novel chemical compounds.  As mentioned in the paper, Linnaeus and Mendel in the 1700s and 1800s had suggested that hybridization could lead to new species, and also in this case, to new metabolites.  7E-polymaxenolide (1), 7E-5-epipolymaxenolide (2), and polymaxenolides A-C (3-5) were identified in this soft coral hybrid.

7E-polymaxenolide (1), 7E-5-epipolymaxenolide (2), and
polymaxenolides A-C7E-polymaxenolide (1), 7E-5-epipolymaxenolide (2), and
polymaxenolides A-C7E-polymaxenolide (1), 7E-5-epipolymaxenolide (2), and
polymaxenolides A-C7E-polymaxenolide (1), 7E-5-epipolymaxenolide (2), and
polymaxenolides A-C

hybrid metabolite

JNP paper

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