Naturalproductman’s Blog

Hey, is that a natural product?!

The Novelty of an Olefin Metathesis Reaction

Posted by naturalproductman on July 31, 2009

Subrata Ghosh and co-workers at the Indian Association for the Cultivation of Science have recently published their progress toward a natural product, Caribenol A in Tetrahedron Letters.  It’s a very interesting entry to making 5,7-bicyclic rings.  I know that olefin metathesis is becoming very common and not as exciting and novel but the olefin metathesis they did in this case involved the opening of the norbornene derivative that gave rise to the five membered ring.

olefin metathesis

TL paper

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