Naturalproductman’s Blog

Hey, is that a natural product?!

Halichondrin

Posted by naturalproductman on October 7, 2009

When an expert in total synthesis such as Kishi has a name on a journal article that is focused on synthesis of natural products, you know it has to be good.  The highlight of this synthesis is really the Ni/Cr catalyzed coupling using an aldehyde and a vinyl iodide.

halichondrin

h2

JACS paper 1

JACS paper 2

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