Naturalproductman’s Blog

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Azo-Methine Ylide Cascade

Posted by naturalproductman on March 1, 2010

Guillame Belanger and co-workers at Universite de Sherbrooke in Canada have recently published in Organic Letters on a cascade cyclization that requires an formamide tethered by an allyl silane, which generates an azomethine ylide, which in turn undergoes a cyclization process to yield a bicyclic compound.

OL paper

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