Naturalproductman’s Blog

Hey, is that a natural product?!

Azo-Methine Ylide Cascade

Posted by naturalproductman on March 1, 2010

Guillame Belanger and co-workers at Universite de Sherbrooke in Canada have recently published in Organic Letters on a cascade cyclization that requires an formamide tethered by an allyl silane, which generates an azomethine ylide, which in turn undergoes a cyclization process to yield a bicyclic compound.

cascade
OL paper

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

 
%d bloggers like this: