Naturalproductman’s Blog

Hey, is that a natural product?!

Taxol Studies

Posted by naturalproductman on March 16, 2010

Rudiger Kaspera, Rodney Croteau and co-workers at Washington State University have recently published in Tetrahedron Letters on an in vitro study of taxol’s oxetane ring formation by synthesizing radiolabeled potential taxol substrates.  However, none of the surrogate substrates synthesized underwent rearrangement to form the oxetane ring.

taxol

TL paper

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

 
%d bloggers like this: