Naturalproductman’s Blog

Hey, is that a natural product?!

Ring Contraction of Taxol

Posted by naturalproductman on March 22, 2010

T. Narender and co-workers at the Central Drug Research Institute in India have recently reported in the Journal of Natural Products of all places, on a novel contraction of the six membered ring in taxol to a five membered ring using BF3 etherate.

ring contraction

JNP paper

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