Naturalproductman’s Blog

Hey, is that a natural product?!

Linderol A Synthesis

Posted by naturalproductman on March 24, 2010

Hatice Berber and co-workers at CNRS have recently reported in JOC on the synthesis of linderol A.  They made the dihydrobenzofuran moiety via ring opening of an epoxide with a phenolic nucleophile.  This paper is the first one I’ve seen that showed the pictures of the TLC plates – they wanted to show that the rotamers can be separated by TLC at -20 degrees Celsius.

rotamers

JOC paper

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

 
%d bloggers like this: