Naturalproductman’s Blog

Hey, is that a natural product?!

Making Enones

Posted by naturalproductman on April 12, 2010

The benzoin condensation takes advantage of umpolung chemistry where the aldehyde, which is normally an electrophile, is used as a nucleophile.  Frank Glorius and co-workers from Organisch-Chemisches Institut der Westfalischen Wilhelms-Universitat Munster have made use of this umpolung reactivity and used an alkyne as the reactant with the aldehyde.

JACS paper


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: