Naturalproductman’s Blog

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Isolysergol Synthesis

Posted by naturalproductman on May 12, 2010

Stephen Martin and co-worker at UT Austin have published in Organic Letters on an asymmetric synthesis of isolysergol via an enantioselective ring closing metathesis reaction to afford the dihydropiperidine ring.  They used a chiral molybdenum catalyst for the ring closing metathesis reaction.

OL paper


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