Naturalproductman’s Blog

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Two Step Access to Substituted Amino-pyrroles

Posted by naturalproductman on June 27, 2010

Takeo Konakahara and co-workers at the Tokyo University of Science have reported in the European Journal of Organic Chemistry on a multicomponent approach to synthesize aza dienes and followed by a ytterbium catalyzed [4+2] reaction between the azadiene and TMS-cyanide.

azadiene

European JOC paper

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