Naturalproductman’s Blog

Hey, is that a natural product?!

Ugi then Staudinger-Aza-Wittig

Posted by naturalproductman on July 27, 2010

Tomas Torroba and co-workers from the Universidad de Burgos have published on an Ugi reaction followed by a Staudinger-Aza-Wittig cyclization.  The key was that the carboxylic acid partner in the Ugi reaction was tethered by an azide group.

cascade

Tetrahedron paper

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

 
%d bloggers like this: