Naturalproductman’s Blog

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Grob Fragmentation to Subsituted Piperidines

Posted by naturalproductman on October 15, 2010

Andre Charette and co-worker at the University of Montreal in Canada have published in JOC on a Grob fragmentation approach to access a substituted piperidine, which in turn was used as a precursor for an indolizidine.

Grob fragmentation

 

JOC paper

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