Synthesis of Merrilactone
Posted by naturalproductman on October 22, 2010
Michael Greaney and co-workers at the University of Edinburgh have published on the racemic synthesis of merrilactone. One of the highlights is a radical cascade that involves the use of a titanium reagent on an epoxy alkyne substrate, which undergoes an epoxide opening and a 5-exo dig cyclization.
This entry was posted on October 22, 2010 at 7:23 am and is filed under Cascade Reactions, Diseases, Methodology, Neurodegenerative, Radical Chemistry, Titanium, Transition Metal. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.