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Reformatsky-Claisen Cascade

Posted by naturalproductman on November 19, 2010

Jeffrey Johnson and co-workers at UNC have published in JACS on a Refoormatzky-Claisen condensation cascade reaction where the second enolate generated opens a beta-lactone.

beta lactone

This entry was posted on November 19, 2010 at 7:17 am and is filed under Cascade Reactions, Claisen condensation, Methodology, Multi-Component Coupling, Named Reactions, Reformatsky, Ring Opening, Transition Metal, Zinc. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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