Naturalproductman’s Blog

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Sterol Glycosides

Posted by naturalproductman on December 7, 2010

Julia Kubanek and co-workers at Georgia Institute of Technology have published in Bioorganic and Medicinal Chemistry on the isolation of sterol glycosides, 19-O-β-d-glucopyranosyl-19-hydroxy-cholest-4-en-3-one (1) and 19-O-β-d-N-acetyl-2-aminoglucopyranosyl-19-hydroxy-cholest-4-en-3-one (2), which were collected from the Fijian red alga Peyssonnelia sp.  and had biological activity against human breast cancer cell lines MDA-MB-468 with IC50 = 0.71 and 0.86 μM, respectively.

sterol glycosides

 

BMC paper

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