Naturalproductman’s Blog

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A Cool Cascade

Posted by naturalproductman on January 10, 2011

Chi-Sing Lee and co-workers at Peking University have published in Organic Letters on a cascade reaction that leads to 5,6-bicyclic rings.  This reaction catalyzed by zinc (II) bromide involves a Diels-Alder reaction followed by a reaction that looks like the Conia-ene reaction.

bicycles

 

OL paper

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