Naturalproductman’s Blog

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Crinine Synthesis

Posted by naturalproductman on January 24, 2011

Xiaodong Yang and co-workers at Yunnan University have published in Synlett on their formal synthesis of crinine.  The seven membered ring with an exocyclic methylene was synthesized by an intramolecular Heck reaction.

seven membered

 

Synlett paper

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