Naturalproductman’s Blog

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Hydroxymethylcytosine can get attacked.

Posted by naturalproductman on January 26, 2011

Saulius Klimasauskas and co-workers at Vilnius University in Lithuania have published in ACIEE on an enzyme mechanism study where they looked at what this enzyme, DNA cytosine-5-methyl transferase, would do to hydroxymethylcytosine in the presence of a nucleophilic molecule such as a thiol.

thiol

ACIEE paper

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