Naturalproductman’s Blog

Hey, is that a natural product?!

Benzyne mcr

Posted by naturalproductman on May 27, 2011

Hideto Miyabe and co-workers from Hyogo University have reported in ACIEE on a multicomponent reaction between benzynes, DMF and beta-ketoesters or 1,3-diketones to afford 2H-chromene or isocoumarin derivatives.

acetate

ACIEE paper

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