Naturalproductman’s Blog

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(8R)-3β,8-Dihydroxypolypoda-13E,17E,21-triene

Posted by naturalproductman on August 10, 2011

Thomas Simmet and co-workers from Ulm University have reported in the Journal of Natural Products on the isolation of (8R)-3β,8-Dihydroxypolypoda-13E,17E,21-triene from the oleogum resin of P. lentiscus.  This compound had inhibitory activity against androgen-insensitive prostate cancers (~10 micromolar).

prostate

JNP paper

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