Naturalproductman’s Blog

Hey, is that a natural product?!

FL-120B’ via Friedel Crafts

Posted by naturalproductman on August 31, 2011

John Porco and co-worker at Boston University have reported in ACIEE on the synthesis of epoxykinamycin FL-120B’ with the key step being an intramolecular Friedel-Crafts acylation to form the five membered ring.

epoxy

ACIEE paper

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