Naturalproductman’s Blog

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Bielschowskysin core

Posted by naturalproductman on April 17, 2012

Johann Mulzer and co-workers at the University of Vienna have reported in Organic Letters on the synthesis of the tricyclic core of bielschowskysin.  Surprisingly, that cyclobutane with the five membered ring is stable in many different conditions (ie:  LiOH).

cyclobutane

OL paper

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