John Porco and co-workers have reported in JACS on the synthesis of eliptifoline and ponapensin.
Archive for July, 2012
Eliptifoline and ponapensin syntheses
Posted by naturalproductman on July 31, 2012
Posted in Cascade Reactions, Light Mediated, Methodology, Total Synthesis | Leave a Comment »
Heronapyrrole C synthesis
Posted by naturalproductman on July 20, 2012
Christian Stark and colleague at the Universitat Hamburg have reported in Organic Letters on the synthesis of heronapyrrole C.
Posted in Alkaloids, Asymmetric, Methodology, Tetrahydrofuran, Total Synthesis | Leave a Comment »
Shi epoxidation approach for glabrescol
Posted by naturalproductman on July 20, 2012
Jin Qu and co-workers from Nankai University have reported in Organic Letters on a synthesis of a polytetrahydrofuranyl compound using Shi epoxidation of a polyolefin intermediate.
Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Polyenes, Shi epoxidation, Tetrahydrofuran, Total Synthesis | Leave a Comment »
Lactone and allene radical cyclization
Posted by naturalproductman on July 20, 2012
David Procter and co-workers from the University of Manchester have reported in JACS on a SmI2-mediated radical cyclization of a lactone bearing an allene to form a 5,7-bicyclic ring system.
Posted in Allenes, Methodology, Radical Chemistry, Seven-Membered Rings | Leave a Comment »
Lannotinidine B synthesis
Posted by naturalproductman on July 17, 2012
Zhu-jun Yao and co-workers from Nanjing University have reported in JACS on a synthesis of lannotinidine B.
Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | 1 Comment »
Interrupted Ugi reaction
Posted by naturalproductman on July 16, 2012
Erik Sorensen and co-workers have reported in Chemical Science on their synthesis of 11-methoxy mitragynine.
Posted in Alkaloids, Cascade Reactions, Methodology, Named Reactions, Ugi | Leave a Comment »
Gambieric acid A synthesis
Posted by naturalproductman on July 16, 2012
Makoto Sasaki and co-workers at Tohoku University have reported in JACS on the synthesis of gambieric acid A.
Posted in Cascade Reactions, Methodology, Polyether | Leave a Comment »
AM-8553 synthesis
Posted by naturalproductman on July 16, 2012
Brian Lucas and co-workers from Amgen in South San Francisco have reported in JACS on the synthesis of AM-8553, which involved some 18O-labeling,
Posted in Cancer, Cascade Reactions, Methodology | Leave a Comment »
Isoschizogamine synthesis
Posted by naturalproductman on July 13, 2012
Tohru Fukuyama and co-workers at the University of Tokyo have reported in JACS on the synthesis of isoschizogamine.
Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »