Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for May, 2013

[3,3]-Sigmatropic

Posted by naturalproductman on May 9, 2013

Laszlo Kurti and co-workers from UT Southwestern have reported in JACS on a [3,3]-sigmatropic rearrangement approach to access BINAM derivatives using a phosphoric acid catalyst.

organocatalyst

JACS paper

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Posted in Asymmetric, Computational, DFT, Methodology, Organocatalytic | Leave a Comment »

Rhizopodin synthesis

Posted by naturalproductman on May 8, 2013

Ian Paterson and co-workers from the University of Cambridge have reported in ACIE on the synthesis of rhizopodin.

rhizopodin

ACIE paper

Posted in Macrolides, Methodology, Oxazoles, Total Synthesis | Leave a Comment »

Oxazoles to pyridines

Posted by naturalproductman on May 7, 2013

Pierre Yves-Renard and co-workers from CNRS have reported in Organic Letters on an interesting synthesis of pyridines.

pyridines

OL paper

Posted in Cascade Reactions, Mechanistic, Methodology | 1 Comment »

Which point group is that organocatalyst?

Posted by naturalproductman on May 7, 2013

Hiromichi Fujioka and co-workers from Osaka University have reported in Organic Letters on a kinetic resolution of a  bromo-carboxylic acid using a C3-symmetric organocatalyst.

C3

OL paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

Endoperoxide rearrangement

Posted by naturalproductman on May 7, 2013

Ihsan Erden and co-workers at SFSU have reported in Tetrahedron on an endoperoxide rearrangement.

rearrangement

Tetrahedron paper

Posted in Mechanistic, Methodology | Leave a Comment »

Looks like guanacastepene

Posted by naturalproductman on May 7, 2013

Asperterpenols A and B were isolated from a mangrove fungus.

asperterpenol

OL paper

Posted in Sesterterpenes, Sesterterpenoids | Leave a Comment »

Chiral enolates

Posted by naturalproductman on May 7, 2013

Takeo Kawabata and co-workers from Kyoto University have reported in JACS on the generation of chiral enolates to form chiral carbon centers.

chiral enolates

JACS Paper

Posted in Asymmetric, Methodology | Leave a Comment »

N,N-Diphenylaminomethylene block

Posted by naturalproductman on May 7, 2013

Keiji Maruoka and co-workers have reported in JACS on an approach to form an alpha-quaternary chiral carbon center.

chiral

JACS paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

Triazole annulation

Posted by naturalproductman on May 7, 2013

Huw Davies and colleague from Emory University have reported in JACS on an indole annulation using a triazole.
indole

JACS paper

Posted in Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

Hydrocarbamoylation

Posted by naturalproductman on May 7, 2013

Erick Carreira and colleague have reported in JACS on a ruthenium catalyzed hydrocarbamoylation.

ruthenium
JACS paper

Posted in Methodology, Ruthenium, Transition Metal | Leave a Comment »