Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for July, 2013

Participating in study sections

Posted by naturalproductman on July 26, 2013

Here’s an informational packet about study sections from the HHMI website.

Posted in Links, Random | Leave a Comment »

KR by NHC

Posted by naturalproductman on July 24, 2013

Kenichi Yamada and co-workers at Kyoto University have reported in JACS on a kinetic resolution approach to resolve 1,2-diols.
NHC

JACS paper

Posted in Asymmetric, Kinetic resolution, Methodology, Organocatalytic | Leave a Comment »

Overbred intermediates

Posted by naturalproductman on July 24, 2013

Phil Baran and co-workers have reported in ACIE on the synthesis of steviol by using “overbred” intermediates, a term coined by Hoffman in 2009 referring to intermediates in a synthetic route that contain one or more C-C bond(s) that will break to get to the target product.

overbred

ACIE paper

Posted in Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

C-P bond from a C-H bond

Posted by naturalproductman on July 24, 2013

Masahiro Murakami and co-workers have reported in ACIE on a C-P bond formation.

C-H

ACIE paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

C-H activation

Posted by naturalproductman on July 24, 2013

Nobuharu Iwasawa and co-workers at Tokyo Institute of Technology have reported in JACS on a palladium catalyzed CO2 fixation reaction to form coumarins from a vinyl phenol.

coumarin

JACS paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

Altmetric Score

Posted by naturalproductman on July 22, 2013

Anyone notice something new on ACIE abstracts?  They have this thing called the altmetric score where they count how many times people tweet about the articles or post on facebook or mention on Google+.

 

Am score

Posted in Ethics, Random | Leave a Comment »

Indotertine A and Drimentines A, F, and G syntheses

Posted by naturalproductman on July 22, 2013

Ang Li and co-workers at SIOC have reported in ACIE on syntheses of indotertine A and drimentines A, F, and G.

alkaloids

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Syntheses of (±)-Spiroquinazoline, (−)-Alantryphenone, (+)-Lapatin A, and (−)-Quinadoline B

Posted by naturalproductman on July 22, 2013

Dawei Ma and colleague at SIOC have reported in ACIE on the syntheses of

alkaloids

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Relevance and Design (Conception) are important to publish in ACIE

Posted by naturalproductman on July 22, 2013

An interesting study was done on rejected manuscripts from ACIE by Lutz Bornmann and co-workers at ETH Zurich.

They concluded that the “relevance of contribution” (i.e. “future gain” that comes from the publication) and “design/conception” (i.e. reproducibility, design of research experiments) are important factors that led to a rejected paper from ACIE to be published in another high impact journal.

Scientometrics paper

Posted in Ethics, Random | Leave a Comment »

Posted by naturalproductman on July 21, 2013

Stephen Martin and co-workers have reported in JACS on a synthesis of citirnadin A.

citrinadin A

JACS paper

Posted in Alkaloids, Asymmetric, Methodology, Stereochemistry, Structural Reassignment, Total Synthesis | Leave a Comment »