Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for February, 2014

Benzyne chemistry for tubingensin A

Posted by naturalproductman on February 19, 2014

Neil Garg and co-workers have reported in JACS on the synthesis of tubingensin A. An interesting [2+2] reaction occurred between a benzyne and an enolate.

2+2

JACS paper

Posted in Alkaloids, benzyne, Cascade Reactions, Methodology | Leave a Comment »

Podophyllotoxin synthesis

Posted by naturalproductman on February 19, 2014

Thomas Maimone and colleague have reported in ACIE on the synthesis of podophyllotoxin.

podophyllotoxin

ACIE paper

Posted in C-H activation, Methodology, Total Synthesis | Leave a Comment »

Sculponeatin N synthesis

Posted by naturalproductman on February 19, 2014

Regan Thomson and co-workers from Northwestern have reported on the synthesis of sculponeatin N.

alkaloid

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Secalonic acids A and D

Posted by naturalproductman on February 19, 2014

John Porco and colleague have reported in ACIE on the synthesis of secalonic acids A and D.

dimer

ACIE paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Leiodermatolide synthesis

Posted by naturalproductman on February 19, 2014

Ian Patterson and co-workers have reported in ACIE on the synthesis of leiodermatolide.

synthesis

ACIE paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Aspidophylline A synthesis

Posted by naturalproductman on February 2, 2014

Dawei Ma and co-workers have reported in ACIE on the synthesis of aspidophylline A.

aspidophylline A

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Leiodermatolide synthesis

Posted by naturalproductman on February 2, 2014

Ian Paterson and co-workers at the University of Cambridge have reported in ACIE on the synthesis of leiodermatolide.

macrolide

ACIE paper

Posted in Macrolides, Methodology, Total Synthesis | Leave a Comment »