Naturalproductman’s Blog

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Hydroamination of 1,3-dienes

Posted by naturalproductman on April 25, 2014

Simon Meek and co-workers from UNC Chapel Hill have reported in JACS on an intermolecular hydroamination of 1,3-diene substates. Nice to see an intermolecular case, I think people usually  use platinum based catalysts for this – but my experience was not good using some platinum siloxy complex. User friendliness is always a good method.

hydroamination

JACS paper

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