Naturalproductman’s Blog

Hey, is that a natural product?!

Pd-catalyzed C-N bond formation

Posted by naturalproductman on June 5, 2014

Matthew Gaunt and co-workers from the University of Cambridge have reported in Nature on a palladium catalyzed intramolecular C-N bond formation from C-H bonds. I am reminded of the ACIE paper from Frances Arnold’s group at Caltech where they used a P450 mutant to do a similar reaction.


Nature paper


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