Naturalproductman’s Blog

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Archive for January, 2015

Gold vinylidene = Intramolecular C-H activation

Posted by naturalproductman on January 23, 2015

Jose Gonzalez and co-workers from the University of Oviedo have reported in ACIE on a gold vinylidene approach for intramolecular C-H activation.

gold vinylidine

ACIE paper

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Posted in Cascade Reactions, Gold, Methodology, Transition Metal | Leave a Comment »

Caprazamycin A synthesis

Posted by naturalproductman on January 23, 2015

Yoshiji Takemoto and co-workers from Kyoto University have reported in ACIE on the synthesis of caprazamycin A.

caprazamycin

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Rhenium vinylidene

Posted by naturalproductman on January 23, 2015

Kazuhiko Takai and co-workers from Okayama University have reported in JACS on a rhenium vinylidine approach to form C-C bonds between a terminal alkyne and a methanetricarboxylate.

rhenium

JACS paper

Posted in Methodology, Rhenium, Transition Metal | Leave a Comment »

Yezo’otogirin C synthesis

Posted by naturalproductman on January 18, 2015

Chi-Sing Lee and co-workers from Peking University have reported in JOC on the synthesis of yezo’otogirin C. yezo-otogirin C

JOC paper

Posted in Methodology, Total Synthesis | Leave a Comment »

Brazilin synthesis

Posted by naturalproductman on January 18, 2015

Ikyon Kim and colleague from Yonsei University have reported in JOC on the synthesis of brazilin.

brazilin

JOC paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Sigmatropic rearrangements

Posted by naturalproductman on January 18, 2015

Matthew Cook and co-workers from Queen’s University Belfast in the UK have reported in JOC on some interesting sigmatropic reactions, depending on the base used, an isomerization Claisen occurs or a [2,3]-Wittig-anionic oxy-Cope rearrangement occurs.
rearrangement
JOC paper

Posted in Mechanistic, Methodology, Pericyclic reactions, Sigmatropic Rearrangements | Leave a Comment »

Galanthamine and lycoramine formal synthesis

Posted by naturalproductman on January 18, 2015

Zhi-Xiang Yu and colleague at BNLMS have reported in JOC on a formal synthesis of galanthamine and lycoramine.

galanthamine

JOC paper

Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Salinipostins

Posted by naturalproductman on January 18, 2015

Roger Linington and co-workers from UCSC have reported in JOC on the isolation of salinipostins.

salinipostins
JOC paper

Posted in Diseases, Malaria, Phosphates | Leave a Comment »

Phyllospongin D has a cyclobutane

Posted by naturalproductman on January 18, 2015

Rabab Mohammed and co-workers from Beni-Suef University in Egypt have reported in Tetrahedron on the isolation of some sesterterpenes from an Egyptian marine sponge.

sesterterpenes

Tetrahedron paper

Posted in Sesterterpenes | Leave a Comment »

A few oxindoles

Posted by naturalproductman on January 18, 2015

Shuhua Qi and co-workers from CAS have reported in Tetrahedron on the isolation of cyclopiamides B-J.

oxindoles

Tetrahedron paper

Posted in Alkaloids, Indoles | Leave a Comment »