Naturalproductman’s Blog

Hey, is that a natural product?!

Sn2 prime with trichloroacetimidates

Posted by naturalproductman on May 28, 2015

At first look of the abstract figure I thought this was an Overman rearrangement paper but no, trichloroacetimidates are also good leaving groups for Sn2 prime reactions.

Sn2 prime

ACIE paper

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