Naturalproductman’s Blog

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Coupling between boron and silyl enolates (not a Mukaiyama-Michael)

Posted by naturalproductman on August 6, 2015

At first glance, I thought it was a Mukaiyama-Michael reaction with the silyl enol ether to form a dicarbonyl product, but then you look carefully and see that the product is a 1,4-dicarbonyl (not 1,5-dicarbonyl) and the other reactant is a boron enolate.
enol

JACS paper

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