Naturalproductman’s Blog

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Pyridimidine through multi-component coupling

Posted by naturalproductman on October 1, 2015

Rhett Kempe and co-workers from Universität Bayreuth have reported in JACS on an iridium catalyzed multi-component approach to synthesize pyrimidines from an amidine and three different alcohols.

pyrimidine

JACS paper

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