Naturalproductman’s Blog

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Asymmetric Passerini reaction

Posted by naturalproductman on November 3, 2015

When I saw the Passerini reaction in the title, I thought of the use of an Ugi reaction in the synthesis of dysibetaine by the Kobayashi group. Bin Tan and co-workers at South University of Science and Technology in China have reported in JACS on a phosphoric acid catalyzed Passerini reaction.

Passerini

JACS paper

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