Naturalproductman’s Blog

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Prostaglandin E2 methyl ester synthesis

Posted by naturalproductman on February 15, 2016

Minoru Isobe and co-workers from National Tsing Hua University have reported in JOC on a synthesis of PGE2 methyl ester using a very nice cascade cyclization.

PGE methyl ester Isobe JOC

 

JOC paper

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