Naturalproductman’s Blog

Hey, is that a natural product?!

Olefin difluorinations are in

Posted by naturalproductman on April 7, 2016

Ryan Gilmour and colleague at Westfal̈ische Wilhelms-Universitaẗ Münster have reported in JACS on a difluorination of an olefin using p-iodotoluene, selectfluor, and various sources of amine-HF including TREAT-HF (triethylamine trihydrofluoride). They also try to expand on the transformation by making it asymmetric using a C2-symmetric chiral aryl iodide.


JACS paper


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: