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Markovnikov addition – terminal alkynes to ketones

Posted by naturalproductman on April 19, 2016

Chao-Jun Li and co-workers from McGill University reported in Organic Letters on a useful transformation that converts a terminal alkyne to a ketone using trifluoroethanol as the solvent and triflic acid.

This entry was posted on April 19, 2016 at 4:47 am and is filed under Alkynes, Cascade Reactions, Methodology. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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