Naturalproductman’s Blog

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Archive for the ‘Alkaloids’ Category

Serpentine synthesis

Posted by naturalproductman on May 2, 2015

Karl Scheidt and co-workers have reported in ACIE on the synthesis of alstonine and serpentine through cooperative catalysis.
heteroyohimbine
ACIE paper

Posted in Alkaloids, Cooperative Catalysis, Methodology, Total Synthesis | Leave a Comment »

Mycoleptodiscin A synthesis

Posted by naturalproductman on April 26, 2015

Ang Li and co-workers from SIOC have reported in ACIE on the synthesis of mycoleptodiscin A.

mycoleptodiscin
ACIE paper

Posted in Alkaloids, Steroids, Total Synthesis | Leave a Comment »

Eudistidine A

Posted by naturalproductman on April 20, 2015

The NCI does some nice work with natural products. Kirk Gustafson and co-workers at Bethesda have reported in JACS on some new natural products that block the interaction between p300 and HIF1alpha.

70

JACS paper

Posted in Alkaloids, Protein-Protein Interaction, Proteins, Total Synthesis | Leave a Comment »

Galanthamine and lycoramine syntheses

Posted by naturalproductman on April 12, 2015

Yanxing Jia and co-workers at Peking University have reported in ACIE on the synthesis galanthamine and lycoramine.
galanthamine

ACIE paper

Posted in Alkaloids, Asymmetric, Methodology, Total Synthesis, Transition Metal | Leave a Comment »

Paspaline synthesis

Posted by naturalproductman on April 12, 2015

Jeffrey Johnson and colleague at UNC have reported in JACS on the synthesis of paspaline.
paspaline

JACS paper

Posted in Alkaloids, Cascade Reactions, Total Synthesis | Leave a Comment »

Deethylibophyllidine and limaspermidine syntheses

Posted by naturalproductman on March 25, 2015

Chun-An Fan and co-workers from Lanzhou University have reported in JACS on the synteses of deethylibophyllidine and limaspermidine.

alkaloid

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Cycloclavine biosynthesis

Posted by naturalproductman on March 5, 2015

Sarah O’Connor and co-workers from the John Innes Centre in the UK have reported in ACIE on the biosynthesis of cycloclavine.

cycloclavine

ACIE paper

Posted in Alkaloids, Biosynthesis, Enzymatic, Enzymes, Methodology | Leave a Comment »

Dictyodendrin B via C-H activations

Posted by naturalproductman on March 5, 2015

Matthew Gaunt and co-workers at the University of Cambridge have reported in ACIE on the synthesis of dictyodendrin B.
C-H

ACIE paper

Posted in Alkaloids, C-H activation, Methodology, Total Synthesis | Leave a Comment »

Alkaloid 205B synthesis

Posted by naturalproductman on February 10, 2015

Jin Kun Cha and colleague at Wayne State University have reported in JACS on a synthesis of alkaloid 205B.

205

JACS paper

Posted in Alkaloids, Allenes, Methodology, Total Synthesis | Leave a Comment »

Caprazamycin A synthesis

Posted by naturalproductman on January 23, 2015

Yoshiji Takemoto and co-workers from Kyoto University have reported in ACIE on the synthesis of caprazamycin A.

caprazamycin

ACIE paper

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

 
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