Naturalproductman’s Blog

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Archive for the ‘Alkaloids’ Category

Oridamycin synthesis

Posted by naturalproductman on July 22, 2015

Another solo performance from Danishefsky’s lab published by Adam Trotta.

OL paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Penibruguieramine A synthesis

Posted by naturalproductman on July 22, 2015

Sanghee Kim and co-workers from Seoul National University have reported in ACIE on the synthesis of penibruguieramine A.

alkaloid

ACIE paper

Posted in Alkaloids, Asymmetric, Kinetic resolution, Methodology, Total Synthesis | Leave a Comment »

Hosieine A synthesis

Posted by naturalproductman on July 22, 2015

Ran Hong and co-workers at SIOC have reported in ACIE on the synthesis of hosieine A. The pyridone moiety reminds of lyconadin.

alkaloid

ACIE paper

Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Cycloprodigiosin synthesis

Posted by naturalproductman on July 11, 2015

Richmond Sarpong and co-workers have reported in Organic Letters on the synthesis of cyclopropdiogisin. It’s an ACS Editor’s Choice article! Good job!

cycloprodigiosin

OL paper

Posted in Alkaloids, Pyrroles, Total Synthesis | Leave a Comment »

Dragmacidin D synthesis

Posted by naturalproductman on July 1, 2015

I first was introduced to dragmacidins when I started reading work about Stoltz’s group, which was published in JACS, but I didn’t know that Zakarian’s group has also been working on its synthesis and published it in ACIE.

dragmacidin

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Alzmaphorazine B synthesis

Posted by naturalproductman on June 6, 2015

Christopher Vanderwal and colleague have reported in JACS on a synthesis of alzmaphorazine B.

alkaloid

JACS paper

Posted in Alkaloids, Biosynthesis, Total Synthesis | Leave a Comment »

Nodulisporic acid D synthesis

Posted by naturalproductman on June 6, 2015

Amos Smith and co-workers have reported in JACS on the synthesis of nodulisporic acid D.

alkaloid

JACS paper

Posted in Alkaloids, Total Synthesis, Transition Metal | Leave a Comment »

Sarain A synthesis

Posted by naturalproductman on May 12, 2015

Tohru Fukuyama and co-workers at Nagoya University and the University of Tokyo have reported in ACIE on a formal synthesis of sarain A.

sarain

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Gelsemoxonine synthesis

Posted by naturalproductman on May 4, 2015

Erick Carreira and colleague have reported in JACS on the synthesis of gelsemoxonine.

alkaloid

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Serpentine synthesis

Posted by naturalproductman on May 2, 2015

Karl Scheidt and co-workers have reported in ACIE on the synthesis of alstonine and serpentine through cooperative catalysis.
heteroyohimbine
ACIE paper

Posted in Alkaloids, Cooperative Catalysis, Methodology, Total Synthesis | Leave a Comment »

 
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