I thought I was going to have some down time before I posted again, but I ran into this interesting isolation paper of forazoline A that is worth a gander from Tim Bugni’s lab in the University of Wisconsin. They used a 15N-13C HMQC technique to determine which carbon was bonded to which nitrogen, which is apparently the first time this technique was used for a natural product. Looks like a pretty large natural product (m/z 901.4205). They have an interesting looking 13C NMR spectrum of the natural product (13C-labeled) that have splitting patterns on basically all of the carbons of the natural product (and thus looks like a proton NMR).
Archive for the ‘Antifungal’ Category
Posted by naturalproductman on September 10, 2014
Posted by naturalproductman on January 17, 2012
Virginia Lanzotti and co-workers from Università degli Studi di Napoli Federico II in Italy have reported in Phytochemistry on the isolation of antifungal saponins from white onions.