Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Aromatic’ Category

Fijiolide A synthesis

Posted by naturalproductman on August 27, 2015

Nicolai Cramer and colleague from EPFL have reported in JACS on the synthesis of fijiolide A.

fijiolide

JACS paper

Posted in Aromatic, Macrolides, Total Synthesis | Leave a Comment »

Resveratrol binds to human tyrosyl transfer-RNA (tRNA) synthetase

Posted by naturalproductman on March 21, 2015

Paul Schimmel and colleague at Scripps have reported in Nature on a resveratrol target. We all think of red wine when we hear resveratrol.

Nature paper

Posted in Aromatic, Polyketides, Protein Targets | Leave a Comment »

(+)-Procyanidin A2 and (+)-Cinnamtannin B1 syntheses

Posted by naturalproductman on August 18, 2014

Keisuke Suzuki and co-workers from Tokyo Institute of Technology have reported in ACIE on the synthesis of (+)-procyanidin A2 and (+)-cinnamtannin B1.

aromatic

ACIE paper

Posted in Aromatic, Total Synthesis | Leave a Comment »

Cavicularin synthesis

Posted by naturalproductman on August 18, 2014

Christopher Beaudry and colleague at Oregon State have reported in ACIE on the synthesis of cavicularin through a Diels-Alder with a vinyl sulfone dienophile.

Diels Alder

ACIE paper

Posted in Aromatic, Diels-Alder, Methodology, Total Synthesis | Leave a Comment »

Lomaiviticins and DNA damage

Posted by naturalproductman on July 16, 2014

Seth Herzon and co-workers have reported in ACIE on the DNA damage activity of lomaiviticins.

lomaiviticins

ACIE paper

Posted in Aromatic, Chemical Biology | Leave a Comment »

Kuwanons I and J and Brosimones A and B syntheses

Posted by naturalproductman on July 12, 2014

Xiaoguang Lei and co-workers at Peking University have reported in ACIE on the synthesis of kuwanons I and J.
aromatic

ACIE paper

Posted in Antioxidants, Aromatic, Total Synthesis | Leave a Comment »

Vaticanol A synthesis

Posted by naturalproductman on May 22, 2014

Scott Snyder and co-workers from Scripps (Florida) have reported in ACIE on the synthesis of vaticanol A.

vaticanol

ACIE paper

Posted in Aromatic, Methodology, Total Synthesis | Leave a Comment »

Linoxepin synthesis

Posted by naturalproductman on April 18, 2013

Mark Lautens and co-workers at the University of Toronto have reported in ACIE on the synthesis of linoxepin.

linoxepin

ACIE paper

Posted in Aromatic, Polyketides, Total Synthesis | Leave a Comment »

Calvicularin synthesis

Posted by naturalproductman on January 10, 2013

Christopher Beaudry and co-workers from Oregon State have reported in Organic Letters on a synthesis of cavicularin using a vinyl sulfone for a Diels-Alder substrate.

calvicularin

OL paper

Posted in Aromatic, Cascade Reactions, Diels-Alder, Methodology, Named Reactions, Polyketides | Leave a Comment »

HIV-1 reverse transcriptase structure with catechol diether

Posted by naturalproductman on November 19, 2012

Karen Anderson and co-workers at Yale have reported in JACS on a crystal structures of HIV-1 reverse transcriptase with catechol diether drugs.

HIV

JACS paper

Posted in Aromatic, Diseases, Enzymes, HIV, Proteins | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 80 other followers