Kirk Gustafson and co-workers from the NCI have reported in JNP on the isolation of plakinamines N and O.
Archive for the ‘colon’ Category
Plakinamines N and O
Posted by naturalproductman on November 4, 2014
Posted in Alkaloids, Cancer, colon, Steroids | Leave a Comment »
Mollipilins A and B
Posted by naturalproductman on October 25, 2012
Teigo Asai and co-workers from Tohoku University have reported in Organic Letters on the isolation of mollipilins A and B, which had moderate cytotoxicity against human colon cancer cells at 1.8 and 3.7 micomolar IC50 values.
Posted in Cancer, colon, Polyketides | Leave a Comment »
Halichoblelides B and C
Posted by naturalproductman on May 2, 2012
Takeshi Yamada and co-workers at Osaka University of Pharmaceutical Sciences have reported in Tetrahedron on the isolation of some cytotoxic natural products, halichoblelides B and C.
Posted in Cancer, colon, leukemia, Macrolides | Leave a Comment »
Hamamelitannin
Posted by naturalproductman on January 21, 2012
Marta Cascante and co-workers at the Universitat Barcelona have reported in Journal of Natural Products on the isolation of hamamelitannin, which had anti-colon cancer activity.
Posted in Cancer, colon, Tannins | Leave a Comment »
Mollenyne A
Posted by naturalproductman on November 17, 2011
Tadeusz Molinski and colleague at UCSD have reported in Organic Letters on the isolation of mollenyne A which had an IC50 value of 1.3 micrograms/mL against human colon cancer cell lines (HCT-116).
Posted in Cancer, colon, Polyynes | Leave a Comment »
Premnalatifolin A
Posted by naturalproductman on August 26, 2011
Suresh Babu and co-workers at IICT have reported in Tetrahedron Letters on the isolation of a dimeric diterpene dubbed premnalatifolin A from an Indian medicinal plant, Premna latifolia. This compound had IC50 values of 12.15 and 1.11 μg/mL against HT-29 and MCF-7 cell lines, respectively.
Posted in breast, Cancer, colon, Dimer, Diterpene, Seven-Membered Rings | Leave a Comment »
PM050511
Posted by naturalproductman on July 3, 2011
Fernando de la Calle and co-workers at PharmaMar SAU in Spain have reported in JNP on the isolation of some actinopyranones that had anti-cancer activities (PM060431 had 0.38 micromolar GI50 against HT29).
Posted in Actinopyranones, Cancer, colon | Leave a Comment »
Nocardioazines
Posted by naturalproductman on April 26, 2011
Robert Capon and co-workers at the University of Queensland have reported in Organic Letters on the isolation of prenylated diketopiperazines. Nocardioazine A had an IC50 of 59 micromolar against colon cancer cell lines (SW620).
Posted in Alkaloids, Cancer, colon, Piperazines, Polyprenylated | Leave a Comment »
Chabamides from Piper chaba Hunter
Posted by naturalproductman on February 12, 2011
Madhusudana Rao and co-workers at IICT have reported in Tetrahedron on the isolation of chabamides. Chabamide G had an IC50 of 0.018 micrograms/mL against COLO-205 cancer cell line.
Posted in Alkaloids, Cancer, colon | Leave a Comment »
Franklinolides A-C
Posted by naturalproductman on November 17, 2010
Robert Capon and co-workers have published in ACIEE on the isolation of three new polyketide phosphodiesters, franklinolides A-C. Franklinolide A had an IC50 value of 1.7 micromolar against the HT29 (colorectal adenocarcinoma) cancer cell lines.
Posted in Cancer, colon, Polyketides | Leave a Comment »