Naturalproductman’s Blog

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Archive for the ‘HIV’ Category

(±)-Erythro-7′-methylcarolignan E

Posted by naturalproductman on February 2, 2016

Qiong Gu and co-workers from Sun Yat-sen University and UNC have reported in the Journal of Natural Products on the isolation of (±)-erythro-7′-methylcarolignan E with anti-HIV activity.

 

JNP paper

Posted in Diseases, HIV, Lignans | Leave a Comment »

Unciaphenol – Bergman cyclization product of uncialamycin

Posted by naturalproductman on October 16, 2015

Raymond Anderson and co-workers at the University of British Columbia report in Organic Letters on unciaphenol, which has anti-HIV activity.

unciaphenol

OL paper

Posted in Alkynes, Cascade Reactions, Diseases, HIV, Named Reactions, Polyketides | Leave a Comment »

HIV integrase inhibitor synthesis

Posted by naturalproductman on May 12, 2015

Chris Senanayake and co-workers from Boehringer-Ingelheim have reported in ACIE on the synthesis of

HIV

ACIE paper

Posted in Diseases, HIV, Total Synthesis | Leave a Comment »

Efavirenz flow synthesis

Posted by naturalproductman on March 5, 2015

Peter Seeberger and co-workers at Max Planck Institute of Colloids and Interfaces have reported in ACIE on the flow synthesis of efavirenz.

flow

ACIE paper

Posted in Flow, HIV, New Setups, Total Synthesis | Leave a Comment »

Logeracemin A

Posted by naturalproductman on May 21, 2014

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in JACS on the isolation of logeracemin A.

logeracemin A

JACS paper

Posted in Alkaloids, C2-Symmetric, Diseases, HIV | Leave a Comment »

HIV-1 reverse transcriptase structure with catechol diether

Posted by naturalproductman on November 19, 2012

Karen Anderson and co-workers at Yale have reported in JACS on a crystal structures of HIV-1 reverse transcriptase with catechol diether drugs.

HIV

JACS paper

Posted in Aromatic, Diseases, Enzymes, HIV, Proteins | Leave a Comment »

Aetheramides A and B

Posted by naturalproductman on May 29, 2012

Rolf Mueller and co-workers at Universität des Saarlandes have reported in Organic Letters on some anti-HIV depsipeptides with 15 nM IC50 values.

depsipeptides

OL paper

Posted in Depsipeptides, Diseases, HIV | Leave a Comment »

Oxyingenol synthesis

Posted by naturalproductman on April 17, 2012

Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of oxyingenol.

oxyingenol

ACIE paper

Posted in Diseases, Diterpenoids, HIV, Metathesis, Methodology, Ruthenium, Sigmatropic Rearrangements, Total Synthesis, Transition Metal | Leave a Comment »

Anti-HIV schilancitrilactone

Posted by naturalproductman on February 20, 2012

Han-Dong Sun and co-workers from the Kunming Institute of Botany have reported in Organic Letters on the isolation of schilancitrilactones A-C.

schilancitrilactones A-C

OL paper

Posted in Diseases, HIV, Lactones, Nortriterpenoids, Seven-Membered Rings | Leave a Comment »

Daphnane diterpenes

Posted by naturalproductman on January 21, 2012

Matthias Hamburger and co-workers from the University of Basel in Switzerland have reported in JNP on the anti-HIV activities of some daphnane derived natural products.

HIV

JNP paper

Posted in Daphnane, Diseases, Diterpene, HIV | Leave a Comment »

 
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