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Archive for the ‘Diterpene’ Category

Daphnane diterpenes

Posted by naturalproductman on January 21, 2012

Matthias Hamburger and co-workers from the University of Basel in Switzerland have reported in JNP on the anti-HIV activities of some daphnane derived natural products.

HIV

JNP paper

Posted in Daphnane, Diseases, Diterpene, HIV | Leave a Comment »

Cyclomyrsinane

Posted by naturalproductman on January 4, 2012

Judit Hohmann and co-workers at the University of Szeged in Hungary have reported in Tetrahedron on the isolation of

cyclomyrsinane

Tetrahedron paper

Posted in Diterpene | Leave a Comment »

Atropurpuran progress

Posted by naturalproductman on December 14, 2011

Richard Hsung and co-workers have reported in Organic Letters on their progress towards atropurpuran.

atropurpuran

OL paper

Posted in Allenes, Diterpene, Electrocyclization, Methodology, Pericyclic reactions | Leave a Comment »

Obtusinone A

Posted by naturalproductman on December 11, 2011

Chatchanok Karalai and co-workers at Prince of Songkla University have reported in Tetrahedron on an diterpene with anti-inflammatory properties.

obtusinone

Tetrahedron paper

Posted in Anti-inflammatory, Antibiotics, Diterpene | Leave a Comment »

Erogorgiaene synthesis

Posted by naturalproductman on October 2, 2011

Varinder Aggarwal and co-workers at the University of Bristol have reported in JACS on a synthesis of erogorgiaene.

erogorgiaene

JACS paper

Posted in Antibiotics, Aromatic, Diterpene, Methodology, Total Synthesis | Leave a Comment »

Aplyviolene synthesis

Posted by naturalproductman on September 26, 2011

Larry Overman and colleague have reported in JACS on a total synthesis of aplyviolene.  Surprisingly, the bromide in the alpha-bromo enone Michael acceptor substrate did not get displaced.

aplyviolene

JACS paper

Posted in Asymmetric, Cascade Reactions, Conjugate Additions, Diterpene, Methodology, Michael, Named Reactions, Total Synthesis | Leave a Comment »

Pierisformaside C progress

Posted by naturalproductman on September 13, 2011

Craig Williams and co-workers at the University of Queensland have reported in Organic Letters on their progress towards pierisformaside C.

pierisformaside

OL paper

Posted in Cascade Reactions, Diterpene, Methodology, Seven-Membered Rings | Leave a Comment »

Maoecrystal Z synthesis

Posted by naturalproductman on August 30, 2011

Sarah Reisman and co-workers have reported in JACS on a total synthesis of maoecrystal Z featuring a samarium mediated radical redutive cyclization of a dialdehyde intermediate.

maoecrystal Z

JACS paper

 

Isolation paper in OL

Posted in breast, Cancer, Cascade Reactions, Diterpene, leukemia, Methodology, ovarian, Radical Chemistry, Titanium, Transition Metal | Leave a Comment »

Premnalatifolin A

Posted by naturalproductman on August 26, 2011

Suresh Babu and co-workers at IICT have reported in Tetrahedron Letters on the isolation of a dimeric diterpene dubbed premnalatifolin A from an Indian medicinal plant, Premna latifolia.  This compound had IC50 values of 12.15 and 1.11 μg/mL against HT-29 and MCF-7 cell lines, respectively.

diterpene

TL paper

Posted in breast, Cancer, colon, Dimer, Diterpene, Seven-Membered Rings | Leave a Comment »

Diterpenes

Posted by naturalproductman on August 18, 2011

Judit Hohmann and co-workers at the University of Szeged in Hungary have reported in Tetrahedron on the isolation of some diterpenes from a plant called Euphorbia falcata.

diterpenes

Tetrahedron paper

Posted in Diterpene, Esters, Seven-Membered Rings | Leave a Comment »